Plant Transcription Factor Database
Previous version: v3.0
Gossypium hirsutum
NF-YA Family
Species TF ID Description
Gh_A01G1104NF-YA family protein
Gh_A01G1710NF-YA family protein
Gh_A04G0462NF-YA family protein
Gh_A05G0961NF-YA family protein
Gh_A05G1140NF-YA family protein
Gh_A05G3523NF-YA family protein
Gh_A06G0669NF-YA family protein
Gh_A07G0129NF-YA family protein
Gh_A08G0499NF-YA family protein
Gh_A08G1303NF-YA family protein
Gh_A10G0036NF-YA family protein
Gh_A10G0482NF-YA family protein
Gh_A11G2828NF-YA family protein
Gh_A13G1701NF-YA family protein
Gh_A13G1874NF-YA family protein
Gh_D01G1179NF-YA family protein
Gh_D01G1961NF-YA family protein
Gh_D03G0606NF-YA family protein
Gh_D04G0086NF-YA family protein
Gh_D05G1046NF-YA family protein
Gh_D05G1315NF-YA family protein
Gh_D06G0761NF-YA family protein
Gh_D07G2390NF-YA family protein
Gh_D08G1595NF-YA family protein
Gh_D10G0039NF-YA family protein
Gh_D10G0506NF-YA family protein
Gh_D11G3183NF-YA family protein
Gh_D13G2051NF-YA family protein
Gh_D13G2262NF-YA family protein
Gh_Sca006219G01NF-YA family protein
NF-YA Family Introduction

NF-Y transcription factors are likely found in all eukaryotes and have roles in the regulation of diverse genes (McNabb et al., 1995; Edwards et al., 1998; Maity and de Crombrugghe, 1998; Mantovani, 1999). In mammals, where their biochemistry is well described, the NF-Y transcription factor complex is composed of three unique subunits: NF-YA, NF-YB, and NF-YC. Assembly of the NF-Y heterotrimer in mammals follows a strict, stepwise pattern (Sinha et al., 1995, 1996). Initially, a heterodimer is formed in the cytoplasm between the subunits NF-YB and NF-YC. This dimer then translocates to the nucleus, where the third subunit, NF-YA, is recruited to generate the mature, heterotrimeric NF-Y transcription factor (Frontini et al., 2004; Kahle et al., 2005). Mature NF-Y binds promoters with the core pentamer nucleotide sequence CCAAT, and this can result in either positive or negative transcriptional regulation(Peng and Jahroudi, 2002, 2003; Ceribelli et al., 2008).

NF-YA proteins are characterized by the presence of Gln(Q)- and Ser/Thr(S/T)-rich NH2 termini, a subunit interaction domain (NF-YB/NF-YC interaction), and a DNA-binding domain (Olesen and Guarente, 1990; Maity and de Crombrugghe, 1992; Xing et al., 1993, 1994). The protein interaction and DNA binding domains are well conserved between plant and other eukaryote lineages.

Siefers N, Dang KK, Kumimoto RW, Bynum WE 4th, Tayrose G, Holt BF 3rd.
Tissue-specific expression patterns of Arabidopsis NF-Y transcription factors suggest potential for extensive combinatorial complexity.
Plant Physiol, 2009. 149(2): p. 625-41.
PMID: 19019982